Scientists 3-D Print With Human Embryonic Stem Cells

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3-D printers can produce gun parts, aircraft wings, food and a lot more, but this new 3-D printed product may be the craziest thing yet: human embryonic stem cells.

Using stem cells as the “ink” in a 3-D printer, researchers in Scotland hope to eventually build 3-D printed organs and tissues. A team at Heriot-Watt University used a specially designed valve-based technique to deposit whole, live cells onto a surface in a specific pattern.

The cells were floating in a “bio-ink,” to use the terminology of the researchers who developed this technique. They were able to squeeze out tiny droplets, containing five cells or fewer per droplet, in a variety of shapes and sizes. To produce clumps of cells, the team printed out cells first and then overlaid those with cell-free bio-ink, resulting in larger droplets or spheroids of cells. The cells would group together inside these spheroids. Spheroid size is key, because stem cells need certain conditions to work properly. This is why very precisely controlled 3-D printing could be so valuable for stem cell research.

After being squeezed out of a thin valve, the cells were still alive and viable, and able to transform into any other cell in the body, the researchers say. It’s the first time anyone has printed human embyronic stem cells, said lead researcher Will Wenmiao Shu, a professor at Heriot-Watt. But …why?

Eventually, they could be used to print out new tissues, or as filler inside existing organs, which would be regenerated. It could even serve to limit animal testing for new drug compounds, allowing them to be tested on actual human tissue, said Jason King, business development manager at Roslin Cellab, one of the research partners. “In the longer term, [it could] provide organs for transplant on demand, without the need for donation and without the problems of immune suppression and potential organ rejection,” he said in a statement.

Written By: Rebecca Boyle
continue to source article at popsci.com

6 COMMENTS

  1. If they are told to oppose it, they will, no matter if it is (il)logical or (un)reasonable. It doesn’t matter if it is a huge new breakthrough that violates none of their rules, if they are told to oppose it, they will.

  2. This looks like a further development of this work on growing human organs.

    http://ngm.nationalgeographic.com/2011/03/big-idea/organ-regeneration-text

    Solid organs with lots of blood vessels, such as kidneys or livers, are harder to grow than hollow ones like bladders. But Atala’s group—which is working on 22 organs and tissues, including ears—recently made a functioning piece of human liver. One tool they use is similar to an ink-jet printer; it “prints” different types of cells and the organ scaffold one layer at a time. .. . .
    Alt Text

    National Geographic – Bladders

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