










Public Debate on Complexity and Evolution
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2. Comment #61171 by monoape on August 4, 2007 at 2:56 am
3. Comment #61173 by Konradius on August 4, 2007 at 3:00 am
Hah! I could have had first, but at least I started to listen to this event.4. Comment #61176 by Rtambree on August 4, 2007 at 3:25 am
I wish I would have known about this - I would have attended. Where are these type of events announced before they occur? Was it on the Upcoming Events section on the left hand side of this page? I don't recall it being there.5. Comment #61180 by LeeC on August 4, 2007 at 3:32 am
6. Comment #61181 by gcdavis on August 4, 2007 at 3:42 am
7. Comment #61182 by gcdavis on August 4, 2007 at 3:49 am
8. Comment #61183 by rufustfirefly on August 4, 2007 at 4:11 am
I like the "t-shirts".9. Comment #61184 by Ilovelucy on August 4, 2007 at 4:14 am
Monoape, you seem a lot more curmudgeonly than the lovable scamp in your avatar...10. Comment #61191 by Atticus_of_Amber on August 4, 2007 at 5:21 am
11. Comment #61193 by beeline on August 4, 2007 at 5:32 am
12. Comment #61196 by gcdavis on August 4, 2007 at 5:40 am
13. Comment #61199 by Atticus_of_Amber on August 4, 2007 at 5:53 am
14. Comment #61201 by uzi on August 4, 2007 at 6:12 am
RD spends a little time talking about the development of (and precursors to) the wing on his "Growing up in the Universe" DVD. The talks are aimed at children, and it aren't especially deep, but still remain interesting. Surely he has talked about this elsewhere too, though I can't say exactly where. It seems like a safe guess that he would cover it in some depth in at least one of his books.15. Comment #61202 by LeeC on August 4, 2007 at 6:23 am
My question to the panel would be, how do you turn the young on to science?
16. Comment #61203 by BAEOZ on August 4, 2007 at 6:39 am
17. Comment #61206 by Yorker on August 4, 2007 at 7:01 am
18. Comment #61208 by LeeC on August 4, 2007 at 7:19 am
19. Comment #61209 by Yorker on August 4, 2007 at 7:36 am
20. Comment #61216 by icanus on August 4, 2007 at 7:54 am
On a rather more specific point, the last question wasn't answered completely. Take the evolution of a wing, presumably it doesn't offer an evolutionary advantage until it becomes a functioning wing, so what is it the "drives" the intermediate stages, having a couple of "stubs" might even be a disadvantage?
21. Comment #61218 by kaiserkriss on August 4, 2007 at 7:57 am
22. Comment #61219 by LeeC on August 4, 2007 at 7:58 am
23. Comment #61225 by Dr Benway on August 4, 2007 at 8:48 am
24. Comment #61231 by RickM on August 4, 2007 at 9:16 am
25. Comment #61234 by fungaljungle on August 4, 2007 at 9:32 am
RickM26. Comment #61236 by phasmagigas on August 4, 2007 at 9:48 am
27. Comment #61238 by Yorker on August 4, 2007 at 9:59 am
28. Comment #61242 by Zzyx1170 on August 4, 2007 at 10:14 am
Could someone who managed to download it please upload it to rapidshare.com/ and post the rapidshare link here?29. Comment #61265 by Yorker on August 4, 2007 at 12:00 pm
30. Comment #61271 by fungaljungle on August 4, 2007 at 12:21 pm
I'm uploading to RapidShare right now but it's pretty slow, I'l post the link when I get it.
31. Comment #61279 by Yorker on August 4, 2007 at 12:48 pm
32. Comment #61282 by Zzyx1170 on August 4, 2007 at 12:57 pm
Yorker, thank-you for the rapidshare link!33. Comment #61308 by bockman on August 4, 2007 at 2:21 pm
Good man Yorker, thanks for doing that.34. Comment #61312 by CJ22 on August 4, 2007 at 3:02 pm
35. Comment #61314 by Chris Rijk on August 4, 2007 at 3:06 pm
Firstly, many thanks for the rapid-share link!36. Comment #61316 by phasmagigas on August 4, 2007 at 3:18 pm
37. Comment #61323 by phasmagigas on August 4, 2007 at 4:11 pm
38. Comment #61324 by phasmagigas on August 4, 2007 at 4:14 pm
39. Comment #61326 by phasmagigas on August 4, 2007 at 4:33 pm
40. Comment #61335 by Veronique on August 4, 2007 at 6:12 pm
Maybe its not just the nutrition constraint, maybe poor nutrition actually triggers some genetic developmental response in the child to be smaller, and that in turn continues into the next few generations, if food shortages hit past populations for decades than this 'downsizing' could be advantageous. pure speculation on my part, but there it is.
41. Comment #61337 by phasmagigas on August 4, 2007 at 6:24 pm
42. Comment #61349 by PsyPro on August 4, 2007 at 10:48 pm
43. Comment #61351 by PsyPro on August 4, 2007 at 11:08 pm
44. Comment #61354 by Veronique on August 4, 2007 at 11:46 pm
Another theory of pathogenesis is that asthma is a disease of hygiene. In nature, babies are exposed to bacteria and other antigens soon after birth, "switching on" the TH1 lymphocyte cells of the immune system that deal with bacterial infection. If this stimulus is insufficient, as it may be in modern, clean environments, then TH2 cells predominate, and asthma and other allergic diseases may develop. This "hygiene hypothesis" may explain the increase in asthma in affluent populations. The TH2 lymphocytes and eosinophil cells that protect us against parasites and other infectious agents are the same cells responsible for the allergic reaction. Charcot-Leyden crystals are formed when crystalline material in eosinophils coalesce. These crystals are significant in sputum samples of people with asthma. In the developed world, the parasites that eosinophils are programmed to combat are now rarely encountered, but the immune response remains and is wrongly triggered in some individuals by certain allergens.
Other than direct treatments of the symptoms, no cure is presently known for most types of dermatitis; even cortisone treatments and immunomodulation may often have only minor effects on what may be a complex problem. As the condition is often related to family history of allergies (and thus heredity), it is probable that gene therapy or genetic engineering might help.
Damage from the enzymatic activity of allergens is usually prevented by the body's own protease inhibitors, such as, LEKTI, produced from the gene SPINK5. Mutations in this gene are known to cause Netherton's syndrome, which is a congenital erythroderma. These patients nearly always develop atopic disease, including hay fever, food allergy, urticaria and asthma. Such evidence supports the hypothesis that skin damage from allergens may be the cause of eczema, and may provide a venue for further treatment.[17]
Another study identified a gene that the researchers believe to be the cause of inherited eczema and some related disorders. The gene produces the protein filaggrin, the lack of which causes dry skin and impaired skin barrier function.
45. Comment #61360 by gcdavis on August 5, 2007 at 12:45 am
46. Comment #61401 by 601 on August 5, 2007 at 3:42 am
47. Comment #61418 by Yorker on August 5, 2007 at 5:12 am
48. Comment #61422 by Yorker on August 5, 2007 at 5:30 am
49. Comment #61424 by Yorker on August 5, 2007 at 5:39 am
50. Comment #61496 by Veronique on August 5, 2007 at 11:13 am
1. Comment #61168 by Darwin's badger on August 4, 2007 at 2:32 am
Other Comments by Darwin's badger