Breakthrough in delivering drugs to the brain
By JAMES GALLAGHER - BBC NEWS - HEALTH
Added: Mon, 21 Mar 2011 15:30:32 UTC
A new way of delivering drugs to the brain has been developed by scientists at the University of Oxford.
They used the body's own transporters - exosomes - to deliver drugs in an experiment on mice.
The authors say the study, in Nature Biotechnology, could be vital for treating diseases such as Alzheimer's, Parkinson's and Muscular Dystrophy.
The Alzheimer's Society said the study was "exciting" and could lead to more effective treatments.
Research barrier
One of the medical challenges with diseases of the brain is getting any treatment to cross the blood-brain barrier.
The barrier exists to protect the brain, preventing bacteria from crossing over from the blood, while letting oxygen through.
However, this has also produced problems for medicine, as drugs can also be blocked.
In this study the researchers used exosomes to cross that barrier.
Exosomes are like the body's own fleet of incredibly small vans, transporting materials between cells.
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