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To do science, you have to accept that we exist as independent minds in a universe. — my summary of what Weinstein said about what you need to accept to start doing science.

I think it’s more realistic to except that your mind is of a different realm than this physical universe. — CC

That’s fine. To me, science is a part of the universe reflecting on itself, so you can call that a different realm. It’s an attempt to step out of what we are and observe it, something our minds can imagine doing. Weinstein is making a rather simple point, although as we’ve seen here, some people really try to take it and run with it. It’s the philosophical question of how can we know anything, how can you prove we aren’t crazy and just believe we’re sane? You can philosophize about that all day long, but if you want to start doing science, you just accept that you’re not crazy, that you can interrogate the universe and get consistent results that are meaningful, then you get on with it.