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Can you explain to me in detail why the scientific method is the only sure way to acquire knowledge?

I can, but if you sincerely wanted an answer, you would first look it up, then come here for clarification. 

Steven Pinker recently wrote an article for Skeptic.com. It starts by pointing out that you can’t question reason. If you are questioning if reason works, then you are using reason. If you say reason doesn’t work, you have reasons for why you think that. You can question if we exist and if we can evaluate our own knowledge, those questions are purely philosophical. People in the future might be able to look back and explain how we were irrational, or a more intelligent alien species could say it, but we can’t say it about ourselves now.

No, it’s not infallible, because we are fallible. Science is how we deal with who we are  when figuring out what we don’t know.