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Sherlock’s point #3, the lever over the fulcrum of his logic:

“…a scientific explanation for the presence of material quantities cannot exist because there would be no material quantities, but these are required in order to express an explanation…”

Congratulations, you just logically proved that a scientific explanation would have been impossible before anything existed.

Before the advent of material things, (if there were such a condition, e.g., pre-big bang) science did not exist. In fact science could not explain anything without existing itself.

I do not concur with your ridiculous interpolation that therefore science (now that it does exist) can explain nothing.